Difference between revisions of "IolA"

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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU39760]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU39760]
  
* '''E.C. number:'''
+
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.2.1.27 1.2.1.27]
  
 
=== Additional information===
 
=== Additional information===

Revision as of 12:00, 13 May 2009

  • Description: methylmalonate-semialdehyde dehydrogenase (acylating)

Gene name iolA
Synonyms mmsA, yxdA
Essential no
Product methylmalonate-semialdehyde dehydrogenase (acylating)
Function myo-inositol catabolism
MW, pI 53 kDa, 5.139
Gene length, protein length 1461 bp, 487 aa
Immediate neighbours iolB, iolR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MmsA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y. (2008) myo-Inositol catabolism in Bacillus subtilis. J Biol Chem. Apr 18;283(16): 10415-24. PubMed