InfC

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  • Description: translation initiation factor IF-3

Gene name infC
Synonyms
Essential yes PubMed
Product initiation factor IF-3
Function translation
Gene expression levels in SubtiExpress: infC
MW, pI 19 kDa, 10.342
Gene length, protein length 519 bp, 173 aa
Immediate neighbours rpmI, yscA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
InfC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
InfC expression.png
























Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

RplT regulon, stringent response

The gene

Basic information

  • Locus tag: BSU28870

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: IF-3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1TIF (N-terminal domain, Geobacillus stearothermophilus), 1TIG (C-terminal domain, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed