HxlR

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  • Description: transcription activator of the hxlA-hxlB operon

Gene name hxlR
Synonyms yckH
Essential no
Product transcription activator
Function regulation of the ribulose monophosphate pathway
MW, pI 14 kDa, 6.358
Gene length, protein length 360 bp, 120 aa
Immediate neighbours hxlA, srfAA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HxlR context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU03470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: formaldehyde stimulates transcription activation by HxlR
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: hxlR (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

H Yasueda, Y Kawahara, S Sugimoto
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
J Bacteriol: 1999, 181(23);7154-60
[PubMed:10572115] [WorldCat.org] [DOI] (P p)