Difference between revisions of "HmoA"

From SubtiWiki
Jump to: navigation, search
Line 13: Line 13:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of heme
 
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of heme
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU07150 hmoA]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07150 hmoA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.126   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.126   
Line 21: Line 21:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yetF]]'', ''[[yetH]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yetF]]'', ''[[yetH]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12534&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07150 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07150 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07150 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yetG_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yetG_context.gif]]

Revision as of 12:19, 13 May 2013

  • Description: heme monooxygenase

Gene name hmoA
Synonyms yetG
Essential no
Product heme monooxygenase
Function degradation of heme
Gene expression levels in SubtiExpress: hmoA
MW, pI 14 kDa, 9.126
Gene length, protein length 375 bp, 125 aa
Immediate neighbours yetF, yetH
Sequences Protein DNA Advanced_DNA
Genetic context
YetG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HmoA expression.png
























Categories containing this gene/protein

acquisition of iron

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag: BSU07150

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds hemin in vitro with ~1:1 stoichiometry and degrade hemin in the presence of an electron donor PubMed
  • Protein family: antibiotic biosynthesis monooxygenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: hmoA (based on genomic context)
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional references: PubMed