hisS

168

histidyl-tRNA synthetase

locus: BSU_27560

Molecular weight: 47.97 kDa

pI: 5.23

Protein length: 424 aa

Gene length: 1275 bp

function: translation

product: histidyl-tRNA synthetase

essential: yes

ec: 6.1.1.21

synonyms: hisS

List of homologs in different organisms, belongs to COG0124 (Galperin et al., 2021)

Gene

Coordinates: 2,816,535  2,817,809

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Catalyzed reaction/ biological activity

• ATP + L-histidine + tRNA^His --> AMP + diphosphate + H⁺ + L-histidyl-tRNA^His (according to UniProt)

Protein family

• [wiki|Class-II aminoacyl-tRNA synthetase family] (according to UniProt)

Structure

• [PDB|1H4V] (from ''Thermus thermophilus'', 43% identity, 61% similarity) [Pubmed|11399074]
• [AF|O32039]

[wiki|Localization]

• cytoplasm (according to Swiss-Prot)

References

• 19258532,10493797