HepS

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  • Description: heptaprenyl diphosphate synthase component I

Gene name hepS
Synonyms gerCA, hepA
Essential yes PubMed
Product heptaprenyl diphosphate synthase component I
Function menaquinone biosynthesis
MW, pI 28 kDa, 6.273
Gene length, protein length 753 bp, 251 aa
Immediate neighbours menH, mtrB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HepS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HepS expression.png
























Categories containing this gene/protein

biosynthesis of cofactors, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22760

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: All-trans-hexaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-heptaprenyl diphosphate (according to Swiss-Prot)
  • Protein family: Methylisocitrate lyase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References