hepS

hepS
168

heptaprenyl diphosphate synthase component I

locus
BSU_22760
Molecular weight
28.97 kDa
pI
6.27
Protein length
Gene length
function
menaquinone biosynthesis
product
heptaprenyl diphosphate synthase component I (together with [protein|3CAEA54E80A0B56EE120B881C8CDBE055AF6BDC1|hepT])
essential
no
ec
2.5.1.30
synonyms
hepS, gerCA, hepA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,383,615 → 2,384,370
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth [Pubmed|28189581]
essential [Pubmed|12682299], non-essential according to [Pubmed|28189581]
Visit Sartorius.com Visit Sartorius.com
Advertisement
The protein
Catalyzed reaction/ biological activity
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate --> all-trans-heptaprenyl diphosphate + 4 diphosphate (according to UniProt)
Structure
[AF|P31112]
Expression and Regulation
Operons
genes
[gene|C45A5935559F0DAAD70F808725AF730BC18A2B0A|hepS]-[gene|DDD40AEBBCBD3C19661A72B85912E266DBF267B3|menH]-[gene|3CAEA54E80A0B56EE120B881C8CDBE055AF6BDC1|hepT]-[gene|B498ED03F19B7A73878D5C947C28C2A87CAB934D|ndk]
description
[pubmed|22383849]
Open in new tab

[gene|C45A5935559F0DAAD70F808725AF730BC18A2B0A|hepS]→[gene|B498ED03F19B7A73878D5C947C28C2A87CAB934D|ndk]

2024-03-26 00:14:59

Jstuelk

81

4994bd02adb7701a42b6eebb6e0352c9f8a44e38

8B6317CB1523DAD0B462E932EA20388911064C0F

Biological materials
Mutant
BKE22760 (Δ[gene|C45A5935559F0DAAD70F808725AF730BC18A2B0A|hepS]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAAATATCACCCTTGTCC,  downstream forward: _UP4_TAAACCATTATGCAGGACTC
BKK22760 (Δ[gene|C45A5935559F0DAAD70F808725AF730BC18A2B0A|hepS]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAAATATCACCCTTGTCC,  downstream forward: _UP4_TAAACCATTATGCAGGACTC
References
23840410,28189581

C45A5935559F0DAAD70F808725AF730BC18A2B0A

Page visits: 2593

Time of last update: 2024-03-28 22:53:25

Author of last update: Christoph.elfmann