HemA

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  • Description: glutamyl-tRNA reductase

Gene name hemA
Synonyms
Essential no
Product glutamyl-tRNA reductase
Function porphyrin biosynthesis
MW, pI 50 kDa, 5.313
Gene length, protein length 1365 bp, 455 aa
Immediate neighbours hemX, ysxD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HemA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

biosynthesis of cofactors, membrane proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH (according to Swiss-Prot)
  • Protein family: glutamyl-tRNA reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References