Difference between revisions of "Hbs"

From SubtiWiki
Jump to: navigation, search
Line 80: Line 80:
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1HUU 1HUU] (Geobacillus stearothermophilus),  [http://www.rcsb.org/pdb/explore.do?structureId=1EXE 1EXE] (phage SPO1 transcription factor, 45% identity)
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1HUU 1HUU] (Geobacillus stearothermophilus),  [http://www.rcsb.org/pdb/explore.do?structureId=1EXE 1EXE] (phage SPO1 transcription factor, 45% identity)
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42305 P42305]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P08821 P08821]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22790]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22790]

Revision as of 13:21, 20 July 2009

  • Description: non-specific DNA-binding protein Hbsu

Gene name hbs
Synonyms dbpA
Essential yes PubMed
Product non-specific DNA-binding protein Hbsu
Function DNA packaging, function of the signal recognition complex
MW, pI 9 kDa, 9.501
Gene length, protein length 276 bp, 92 aa
Immediate neighbours mtrA, spoIVA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Hbs context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU22790

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: DbpA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Thr-4 PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot), membrane associated PubMed

Database entries

  • Structure: 1HUU (Geobacillus stearothermophilus), 1EXE (phage SPO1 transcription factor, 45% identity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed when no DNA damage is present (LexA) PubMed
  • Regulatory mechanism:
  • Additional information: mRNA is protected from degradation by RnjA by initiating ribosomes PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

Your additional remarks

References