GsiB

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  • Description: general stress protein

Gene name gsiB
Synonyms
Essential no
Product general stress protein
Function unknown
Gene expression levels in SubtiExpress: gsiB
MW, pI 13 kDa, 5.145
Gene length, protein length 369 bp, 123 aa
Immediate neighbours ydbA, ydbB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GsiB context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon, SigI regulon

The gene

Basic information

  • Locus tag: BSU04400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

B Jürgen, T Schweder, M Hecker
The stability of mRNA from the gsiB gene of Bacillus subtilis is dependent on the presence of a strong ribosome binding site.
Mol Gen Genet: 1998, 258(5);538-45
[PubMed:9669336] [WorldCat.org] [DOI] (P p)

B Maul, U Völker, S Riethdorf, S Engelmann, M Hecker
sigma B-dependent regulation of gsiB in response to multiple stimuli in Bacillus subtilis.
Mol Gen Genet: 1995, 248(1);114-20
[PubMed:7651322] [WorldCat.org] [DOI] (P p)

J P Mueller, G Bukusoglu, A L Sonenshein
Transcriptional regulation of Bacillus subtilis glucose starvation-inducible genes: control of gsiA by the ComP-ComA signal transduction system.
J Bacteriol: 1992, 174(13);4361-73
[PubMed:1378051] [WorldCat.org] [DOI] (P p)