grpE

168

heat-shock protein (activation of [protein|30E0AAABB803E577D0D9FBAEF9031319CABD3D89|dnaK])

locus: BSU_25480

Molecular weight: 21.54 kDa

pI: 4.26

Protein length: 187 aa

Gene length: 564 bp

function: control of [protein|30E0AAABB803E577D0D9FBAEF9031319CABD3D89|dnaK] activity

product: heat-shock protein

essential: no

synonyms: grpE

List of homologs in different organisms, belongs to COG0576 (Galperin et al., 2021)

Gene

Coordinates: 2,627,971 → 2,628,534

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The protein

Protein family

• grpE family (single member, according to UniProt)

Structure

• [PDB|4ANI] ([protein|30E0AAABB803E577D0D9FBAEF9031319CABD3D89|dnaK]-[protein|ECAB685E9038DC03FA2CC659112BB07D30DE5C8C|grpE] complex from ''Geobacillus kaustophilus'', 70% identity) [Pubmed|22544739]
• [AF|P15874]

[wiki|Localization]

• Cytoplasm (Homogeneous) [Pubmed|16479537]

Biological materials

Mutant

• BKE25480 (Δ[gene|ECAB685E9038DC03FA2CC659112BB07D30DE5C8C|grpE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTTCACCTCCCTCA,  downstream forward: _UP4_TAATTACATAGCAGGAGGTT
• BKK25480 (Δ[gene|ECAB685E9038DC03FA2CC659112BB07D30DE5C8C|grpE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTTCACCTCCCTCA,  downstream forward: _UP4_TAATTACATAGCAGGAGGTT

labs

• [wiki|Wolfgang Schumann], Bayreuth University, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/schumann_research.htm Homepage]

References

• 10383760,9023197,1339421,16479537,1339421,7592421,22544739,36815589