gmuR

gmuR
168

transcriptional repressor (GntR family) of the [gene|00A4A90685CED4AD46829C45718CF26F1D62F5D3|gmuB]-[gene|44014896157718D3A6190DFDBD663C5CB9DA63FC|gmuA]-[gene|76324E0A6CAA8E1DD0B0C6FAE1CAB402231BF7CC|gmuC]-[gene|D8C81A8768E9C6B47B5E196B54DC2A3A8256E7E6|gmuD]-[gene|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]-[gene|EB6DE119E6FB18413DB2C2B62B114FB787164F74|gmuE]-[gene|35225776F6044513D3E77DBBD6A7A8FE976F506A|gmuF]-[gene|289ACC9D13BBFAA5C083EE525ECCC32DB06E075F|gmuG] operon

locus
BSU_05850
Molecular weight
27.23 kDa
pI
7.44
Protein length
Gene length
function
regulation of glucomannan utilization
product
transcriptional repressor (GntR family)
essential
no
synonyms
gmuR, ydhQ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2188 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
630,170  630,883
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The protein
Protein family
[wiki|GntR family] of transcription factors
[wiki|Domains]
[wiki|HTH gntR-type domain] (aa 1-69) (according to UniProt)
Structure
[PDB|2WV0] (the structure of [protein|6D36D6360FE1CBFF5F64B2A6D1406405D6C6F7D5|nagR], 29% identity) [Pubmed|20047956]
[AF|O05509]
Expression and Regulation
Operons
genes
[gene|00A4A90685CED4AD46829C45718CF26F1D62F5D3|gmuB]-[gene|44014896157718D3A6190DFDBD663C5CB9DA63FC|gmuA]-[gene|76324E0A6CAA8E1DD0B0C6FAE1CAB402231BF7CC|gmuC]-[gene|D8C81A8768E9C6B47B5E196B54DC2A3A8256E7E6|gmuD]-[gene|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]-[gene|EB6DE119E6FB18413DB2C2B62B114FB787164F74|gmuE]-[gene|35225776F6044513D3E77DBBD6A7A8FE976F506A|gmuF]-[gene|289ACC9D13BBFAA5C083EE525ECCC32DB06E075F|gmuG]
description
[Pubmed|18177310]
regulation
induced by cellobiose ([protein|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]) [Pubmed|18177310]
regulatory mechanism
[protein|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]: repression, [Pubmed|18177310], in [regulon|protein:64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|18177310], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: activation, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|18177310], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|00A4A90685CED4AD46829C45718CF26F1D62F5D3|gmuB]→[gene|289ACC9D13BBFAA5C083EE525ECCC32DB06E075F|gmuG]

2024-03-18 05:54:58

Jstuelk

68

1716709ba10a9af523abc0d89eb44ea784dd12d9

42FBC6CD7712CC913DB98C4B417CB4A13C8FAE20

Biological materials
Mutant
MGNA-C192 (ydhQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2190 NBRP B. subtilis, Japan]
BKE05850 ([gene|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGGTATCCTCCGGCAGC,  downstream forward: _UP4_TGATTGCGGAGACAACAAGG
BKK05850 ([gene|64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7|gmuR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGGTATCCTCCGGCAGC,  downstream forward: _UP4_TGATTGCGGAGACAACAAGG
References
18177310,10627040,18177310,20817675,20047956

64CA75A26A08C534EC7ADFC4A6256F07F3D4BFB7

Page visits: 4118

Time of last update: 2024-03-29 04:29:10

Author of last update: Jstuelk