Difference between revisions of "GltT"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
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* '''Structure:''' [http://www.pdb.org/pdb/explore/remediatedSequence.do?structureId=4IZM 4IZM] (the protein from ''Pyrococcus horikoshii'', 35% identity, 73% similarity) {{PubMed|23563139}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O07605 O07605]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O07605 O07605]
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=References=
 
=References=
  
<pubmed>18763711, </pubmed>
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<pubmed>18763711, 23563139 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:58, 20 August 2013

  • Description: major H+/Na+-glutamate symport protein

Gene name gltT
Synonyms yhfG
Essential no
Product major H+/Na+-glutamate symport protein
Function glutamate and aspartate uptake
Gene expression levels in SubtiExpress: gltT
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 45 kDa, 9.029
Gene length, protein length 1287 bp, 429 aa
Immediate neighbours yhfF, yhfH
Sequences Protein DNA DNA_with_flanks
Genetic context
GltT context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GltT expression.png















Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10220

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: View classification (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 4IZM (the protein from Pyrococcus horikoshii, 35% identity, 73% similarity) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Nicolas Reyes, SeCheol Oh, Olga Boudker
Binding thermodynamics of a glutamate transporter homolog.
Nat Struct Mol Biol: 2013, 20(5);634-40
[PubMed:23563139] [WorldCat.org] [DOI] (I p)

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)