GltP

From SubtiWiki
Revision as of 12:53, 2 April 2014 by 134.76.38.147 (talk)
Jump to: navigation, search
  • Description: similar to H+/glutamate symporter

Gene name gltP
Synonyms
Essential no
Product similar to H+/glutamate symporter
Function unknown
Gene expression levels in SubtiExpress: gltP
Metabolic function and regulation of this protein in SubtiPathways:
gltP
MW, pI 44 kDa, 8.651
Gene length, protein length 1242 bp, 414 aa
Immediate neighbours ybfQ, gamP
Sequences Protein DNA DNA_with_flanks
Genetic context
GltP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GltP expression.png















Categories containing this gene/protein

transporters/ other, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02340

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: View classification (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 4KY0 (the glutamate transporter of Thermococcus kodakarensis, 33% identity, 68% similarity) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sonja Jensen, Albert Guskov, Stephan Rempel, Inga Hänelt, Dirk Jan Slotboom
Crystal structure of a substrate-free aspartate transporter.
Nat Struct Mol Biol: 2013, 20(10);1224-6
[PubMed:24013209] [WorldCat.org] [DOI] (I p)

Christopher T Brown, Laura K Fishwick, Binna M Chokshi, Marissa A Cuff, Jay M Jackson, Travis Oglesby, Alison T Rioux, Enrique Rodriguez, Gregory S Stupp, Austin H Trupp, James S Woollcombe-Clarke, Tracy N Wright, William J Zaragoza, Jennifer C Drew, Eric W Triplett, Wayne L Nicholson
Whole-genome sequencing and phenotypic analysis of Bacillus subtilis mutants following evolution under conditions of relaxed selection for sporulation.
Appl Environ Microbiol: 2011, 77(19);6867-77
[PubMed:21821766] [WorldCat.org] [DOI] (I p)

B Tolner, T Ubbink-Kok, B Poolman, W N Konings
Characterization of the proton/glutamate symport protein of Bacillus subtilis and its functional expression in Escherichia coli.
J Bacteriol: 1995, 177(10);2863-9
[PubMed:7751298] [WorldCat.org] [DOI] (P p)