GlnM

• Description: glutamine ABC transporter (membrane protein)
  
  

Gene name	glnM
Synonyms
Essential	no
Product	glutamine ABC transporter (membrane protein)
Function	glutamine uptake
Gene expression levels in SubtiExpress: glnM
Interactions involving this protein in SubtInteract: GlnM
Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate
MW, pI	23 kDa, 8.416
Gene length, protein length	648 bp, 216 aa
Immediate neighbours	glnH, glnP
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins, sporulation proteins

This gene is a member of the following regulons

SigE regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU27450

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GlnQ-(GlnM-GlnP)-GlnH PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O34671

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: glnQ-glnH-glnM-glnP PubMed

• Expression browser: glnM PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • expressed during sporulation (SigE) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Ken-ichi Yoshida, Hirotake Yamaguchi, Masaki Kinehara, Yo-hei Ohki, Yoshiko Nakaura, Yasutaro Fujita
Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box.
Mol Microbiol: 2003, 49(1);157-65
[PubMed:12823818] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)