GerPA

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  • Description: spore germination protein, facilitates access of nutrient germinants to their cognate germinant receptors in spores’ inner membrane

Gene name gerPA
Synonyms yisH
Essential no
Product unknown
Function germination
Gene expression levels in SubtiExpress: gerPA
MW, pI 7 kDa, 4.464
Gene length, protein length 219 bp, 73 aa
Immediate neighbours gerPB, yisI
Sequences Protein DNA DNA_with_flanks
Genetic context
GerPA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GerPA expression.png















Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU10720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: gerPA/gerPF family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed during sporulation in the mother cell (SigK) PubMed
    • subject to negative regulation by GerE PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

J Behravan, H Chirakkal, A Masson, A Moir
Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.
J Bacteriol: 2000, 182(7);1987-94
[PubMed:10715007] [WorldCat.org] [DOI] (P p)