Difference between revisions of "GerKC"

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(This gene is a member of the following regulons)
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''  
 +
** [[GerKA]]-[[GerKB]]-[[GerKC]] (tentative receptor complex)  {{PubMed|21696470}}
 +
** [[GerKC]] is part of the [[germinosome]] in the spore inner membrane {{PubMed|21696470}}
  
* '''Localization:''' cell membrane (according to Swiss-Prot)
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* '''Localization:'''
 +
** spore inner membrane {{PubMed|21696470}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>16707705,16740944,,16352818, </pubmed>
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<pubmed>16707705,16740944,21696470,16352818, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:18, 28 June 2011

  • Description: Nutrient receptor

Gene name gerKC
Synonyms
Essential no
Product Nutrient receptor
Function germination
MW, pI 45 kDa, 9.038
Gene length, protein length 1221 bp, 407 aa
Immediate neighbours gerKA, gerKB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GerKC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

  • Locus tag: BSU03710

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: gerABKC lipoprotein family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Keren K Griffiths, Jingqiao Zhang, Ann E Cowan, Ji Yu, Peter Setlow
Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster.
Mol Microbiol: 2011, 81(4);1061-77
[PubMed:21696470] [WorldCat.org] [DOI] (I p)

Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944] [WorldCat.org] [DOI] (P p)

Takao Igarashi, Peter Setlow
Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors.
J Bacteriol: 2006, 188(11);4131-6
[PubMed:16707705] [WorldCat.org] [DOI] (P p)

Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818] [WorldCat.org] [DOI] (P p)