GcvT

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  • Description: aminomethyltransferase (glycine cleavage system protein T)

Gene name gcvT
Synonyms yqhI
Essential no
Product aminomethyltransferase
(glycine cleavage system protein T)
Function glycine utilization
MW, pI 39 kDa, 5.734
Gene length, protein length 1086 bp, 362 aa
Immediate neighbours gcvPA, yqhH
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
GcvT context.gif
This image was kindly provided by SubtiList






The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by glycine PubMed
  • Regulatory mechanism: induction requires a co-operatively acting riboswitch PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mandal M, Lee M, Barrick JE, Weinberg Z, Emilsson GM, Ruzzo WL, Breaker RR (2004) A glycine-dependent riboswitch that uses cooperative binding to control gene expression. Science 306: 275-279. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed