Difference between revisions of "GbsB"

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* '''Operon:''' '' [[gbsA]]-[[gbsB]]'' {{PubMed|8752328}}
 
* '''Operon:''' '' [[gbsA]]-[[gbsB]]'' {{PubMed|8752328}}
  
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8752328}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gbsB_3183867_3185075_-1 gbsB] {{PubMed|22383849}}
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* '''Sigma factor:''' [[SigA]] {{PubMed|8752328}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 16:06, 16 April 2012

  • Description: choline dehydrogenase (FAD-dependent), glycine betaine synthesis

Gene name gbsB
Synonyms
Essential no
Product choline dehydrogenase (FAD-dependent)
Function osmoprotection
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 43 kDa, 4.912
Gene length, protein length 1209 bp, 403 aa
Immediate neighbours yuaD, gbsA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GbsB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

miscellaneous metabolic pathways, coping with hyper-osmotic stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: An alcohol + NAD+ = an aldehyde or ketone + NADH (according to Swiss-Prot)
  • Protein family: iron-containing alcohol dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

Your additional remarks

References

Additional publications: PubMed

Tamara Hoffmann, Erhard Bremer
Protection of Bacillus subtilis against cold stress via compatible-solute acquisition.
J Bacteriol: 2011, 193(7);1552-62
[PubMed:21296969] [WorldCat.org] [DOI] (I p)

J Boch, B Kempf, R Schmid, E Bremer
Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes.
J Bacteriol: 1996, 178(17);5121-9
[PubMed:8752328] [WorldCat.org] [DOI] (P p)