Difference between revisions of "GatA"

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[[Category:Protein-coding genes]]

Revision as of 08:53, 21 July 2009

  • Description: production of glutamyl-tRNA(Gln)

Gene name gatA
Synonyms yerM, yedB
Essential yes PubMed
Product glutamyl-tRNA(Gln) amidotransferase sununit A
Function translation
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging
MW, pI 52 kDa, 5.24
Gene length, protein length 1455 bp, 485 aa
Immediate neighbours gatC, gatB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GatA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU06680

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate (according to Swiss-Prot)
  • Protein family: amidase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

A W Curnow, K w Hong, R Yuan, S i Kim, O Martins, W Winkler, T M Henkin, D Söll
Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation.
Proc Natl Acad Sci U S A: 1997, 94(22);11819-26
[PubMed:9342321] [WorldCat.org] [DOI] (P p)