Difference between revisions of "GapA"

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(Expression and regulation)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' [[cggR]]-[[gapA]]-[[pgk]]-[[tpiA]]-[[pgm]]-[[eno]][http://dbtbs.hgc.jp/COG/prom/cggR-gapA-pgk-tpiA-pgm-eno.html]
+
* '''Operon:''' [[cggR]]-[[gapA]]-[[pgk]]-[[tpiA]]-[[pgm]]-[[eno]]
 +
* '''Sigma factor:''' SigA
  
* '''Sigma factor:''' SigA [http://dbtbs.hgc.jp/COG/prom/cggR-gapA-pgk-tpiA-pgm-eno.html]
+
* '''Regulation:''' [[CggR]] represses the operon in the absence of glycolytic sugars
  
* '''Regulation:''' [[CggR]] represses the operon in the absence of glycolytic sugars [http://dbtbs.hgc.jp/COG/prom/cggR-gapA-pgk-tpiA-pgm-eno.html]
+
* '''Regulatory mechanism:''' repression
  
* '''Regulatory mechanism:''' repression
+
* '''Database entries:'''  
 +
[http://dbtbs.hgc.jp/COG/prom/cggR-gapA-pgk-tpiA-pgm-eno.html]
  
 
=Biological materials =
 
=Biological materials =

Revision as of 16:44, 12 December 2008

  • Synonyms:
  • Description: glyceraldehyde-3-phosphate dehydrogenase, (NADH-dependent), glycolytic enzyme

The gene

Basic information

  • Coordinates:
  • Gene length:

Phenotypes of a mutant

essential

Database entries

  • DBTBS entry: [1]
  • SubtiList entry:[2]

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: glyceraldehyde-3-phosphate dehydrogenase, (NADH-dependent)
  • Protein family:
  • Paralogous protein(s): GapB

Extended information on the protein

  • Kinetic information
  • Domains
  • Modification Phosphorylation (STY)
  • Effectors of protein activity:
  • Interactions:

HPr(Ser-46-P) binds GapA resulting in a slight inhibition of enzymatic activity.

Crh(Ser-46-P) binds GapA resulting in a slight inhibition of enzymatic activity.

  • Localization

membrane and cytoplasm

Database entries

  • Structure
  • Swiss prot entry
  • KEGG entry

Expression and regulation

  • Regulation: CggR represses the operon in the absence of glycolytic sugars
  • Regulatory mechanism: repression
  • Database entries:

[3]

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:


Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. [4]