Difference between revisions of "GabR"
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| − | * '''Description:''' transcription activator of | + | * '''Description:''' transcription activator of ''[[gabT]]-[[gabD]]'', repressor of ''gabR'' <br/><br/> |
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| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[gabR]]'' (according to [http://dbtbs.hgc.jp/COG/prom/gabR.html DBTBS]) |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12123465}} |
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** GabR: negative autoregulation {{PubMed|12123465}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 19:37, 19 August 2009
| Gene name | gabR |
| Synonyms | ycnF |
| Essential | no |
| Product | transcription regulator |
| Function | regulation of gamma-amino butyric acid utilization |
| MW, pI | 54 kDa, 6.709 |
| Gene length, protein length | 1437 bp, 479 aa |
| Immediate neighbours | yczG, gabT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03890
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94426
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- GabR: negative autoregulation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris R Belitsky
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator.
J Mol Biol: 2004, 340(4);655-64
[PubMed:15223311]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky, Abraham L Sonenshein
GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis.
Mol Microbiol: 2002, 45(2);569-83
[PubMed:12123465]
[WorldCat.org]
[DOI]
(P p)
