Difference between revisions of "GabP"

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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed in the absence of good nitrogen sources (glutamine or ammonium) ([[TnrA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
 
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
 
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[TnrA]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/8951816 PubMed]
  

Revision as of 17:43, 11 June 2009

  • Description: gamma-amino butyric acid permease

Gene name gabP
Synonyms nrg-21
Essential no
Product gamma-amino butyric acid permease
Function utilization of gamma-amino butyric acid
MW, pI 50 kDa, 9.45
Gene length, protein length 1407 bp, 469 aa
Immediate neighbours cotA, yeaB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GabP context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU06310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: View classification (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Brechtel CE, King SC. (1998) 4-Aminobutyrate (GABA) transporters from the amine-polyamine-choline superfamily: substrate specificity and ligand recognition profile of the 4-aminobutyrate permease from Bacillus subtilis. Biochem J. Aug 1;333 ( Pt 3): 565-71. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed