Difference between revisions of "FtsL"
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| − | * '''Description:''' cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring <br/><br/> | + | * '''Description:''' cell-division protein (septum formation), controls together with [[EzrA]] dynamics of the [[FtsZ]] ring <br/><br/> |
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' FtsL is degraded by [[RasP]] |
=Biological materials = | =Biological materials = | ||
Revision as of 17:06, 7 June 2009
- Description: cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring
| Gene name | ftsL |
| Synonyms | ylxB, yllD |
| Essential | yes PubMed |
| Product | cell-division protein |
| Function | septum formation |
| MW, pI | 12 kDa, 10.083 |
| Gene length, protein length | 351 bp, 117 aa |
| Immediate neighbours | mraW, pbpB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU15150
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsL family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: Q07867
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information: FtsL is degraded by RasP
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Pamela Gamba, Jan-Willem Veening, Nigel J Saunders, Leendert W Hamoen, Richard A Daniel
Two-step assembly dynamics of the Bacillus subtilis divisome.
J Bacteriol: 2009, 191(13);4186-94
[PubMed:19429628]
[WorldCat.org]
[DOI]
(I p)
Scott A Robson, Katharine A Michie, Joel P Mackay, Elizabeth Harry, Glenn F King
The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components.
Mol Microbiol: 2002, 44(3);663-74
[PubMed:11994149]
[WorldCat.org]
[DOI]
(P p)
J Sievers, J Errington
The Bacillus subtilis cell division protein FtsL localizes to sites of septation and interacts with DivIC.
Mol Microbiol: 2000, 36(4);846-55
[PubMed:10844672]
[WorldCat.org]
[DOI]
(P p)
