Difference between revisions of "FsrA"

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(Extended information on the RNA)
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* '''Kinetic information'''
 
* '''Kinetic information'''
  
* '''Interactions:''' Binds ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
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* '''[[SubtInteract|Interactions]]:'''
 +
** Binds ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
  
* '''Localization'''
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* '''[[Localization]]'''
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 11:53, 10 August 2011

  • Description: regulatory RNA

Gene name fsrA
Synonyms
Essential no
Product sRNA FsrA
Function inhibition of sdhC translation
Gene length aaa bp
Immediate neighbours ykuI, ykuJ
Gene sequence (+200bp)
Genetic context
FsrA context.jpg



Categories containing this gene/protein

carbon core metabolism, ncRNA

This gene is a member of the following regulons

Fur regulon

The FsrA regulon: citB, leuC-leuD, lutB, sdhC

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry
  • Structure:

Additional information

  • Swiss prot entry:
  • KEGG entry: no entry
  • E.C. number:

Additional information

The RNA

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: hybridizes to sdhC, citB, lutB, and leuC-leuD mRNAs and inhibits their translation. PubMed

Extended information on the RNA

  • Kinetic information

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation: induced by iron starvation (Fur) PubMed
  • Regulatory mechanism: Fur: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:

Labs working on this gene/RNA

John Helmann, Cornell University, USA Homepage

Your additional remarks

References

Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947] [WorldCat.org] [DOI] (I p)