Frr

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  • Description: ribosome recycling factor

Gene name frr
Synonyms
Essential yes PubMed
Product ribosome recycling factor
Function translation
Gene expression levels in SubtiExpress: frr
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 20 kDa, 5.329
Gene length, protein length 555 bp, 185 aa
Immediate neighbours pyrH, uppS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Frr context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Frr expression.png




























Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU16520

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RRF family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)