FrlR

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Gene name frlR
Synonyms yurK
Essential no
Product transcriptional regulator (GntR family)
Function regulation of utilization of sugar amines
Gene expression levels in SubtiExpress: frlR
MW, pI 27 kDa, 6.419
Gene length, protein length 726 bp, 242 aa
Immediate neighbours yurJ, frlD
Sequences Protein DNA DNA_with_flanks
Genetic context
YurK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FrlR expression.png
























Categories containing this gene/protein

utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, transcription factors and their control

This gene is a member of the following regulons

The FrlR regulon:

The gene

Basic information

  • Locus tag: BSU32560

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2IKK (C-terminal domain)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Veronika Maria Deppe, Stephanie Klatte, Johannes Bongaerts, Karl-Heinz Maurer, Timothy O'Connell, Friedhelm Meinhardt
Genetic control of amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR.
Appl Environ Microbiol: 2011, 77(9);2839-46
[PubMed:21398478] [WorldCat.org] [DOI] (I p)

Veronika Maria Deppe, Johannes Bongaerts, Timothy O'Connell, Karl-Heinz Maurer, Friedhelm Meinhardt
Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions.
Appl Microbiol Biotechnol: 2011, 90(2);399-406
[PubMed:21347729] [WorldCat.org] [DOI] (I p)