FrlR

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Gene name frlR
Synonyms yurK
Essential no
Product transcriptional regulator (GntR family)
Function regulation of utilization of sugar amines
Gene expression levels in SubtiExpress: frlR
MW, pI 27 kDa, 6.419
Gene length, protein length 726 bp, 242 aa
Immediate neighbours yurJ, frlD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YurK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FrlR expression.png
























Categories containing this gene/protein

utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, transcription factors and their control

This gene is a member of the following regulons

The FrlR regulon:

The gene

Basic information

  • Locus tag: BSU32560

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2IKK (C-terminal domain)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional references: PubMed

Veronika Maria Deppe, Stephanie Klatte, Johannes Bongaerts, Karl-Heinz Maurer, Timothy O'Connell, Friedhelm Meinhardt
Genetic control of amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR.
Appl Environ Microbiol: 2011, 77(9);2839-46
[PubMed:21398478] [WorldCat.org] [DOI] (I p)

Veronika Maria Deppe, Johannes Bongaerts, Timothy O'Connell, Karl-Heinz Maurer, Friedhelm Meinhardt
Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions.
Appl Microbiol Biotechnol: 2011, 90(2);399-406
[PubMed:21347729] [WorldCat.org] [DOI] (I p)