Difference between revisions of "FrlD"

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(This gene is a member of the following regulons)
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* '''Regulation:'''  
 
* '''Regulation:'''  
 
**'' [[frlB]]'': repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
 
**'' [[frlB]]'': repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
** ''[[frlB]]'': induced in the presence of fructosamine ([[FrlR]]) {{PubMed|21347729}}
+
** ''[[frlB]]'': induced in the presence of fructosamine ([[FrlR]]) {{PubMed|21397556}}
  
 
* '''Regulatory mechanism:'''   
 
* '''Regulatory mechanism:'''   
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
** [[FrlR]]: transcription repression {{PubMed|21347729}}
+
** [[FrlR]]: transcription repression {{PubMed|21397556}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
 
+
'''Additional references:''' {{PubMed|21397556}}
 
<pubmed>15556630,16153181, 21347729,12618455, 12823818 </pubmed>
 
<pubmed>15556630,16153181, 21347729,12618455, 12823818 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:24, 17 March 2011

  • Description: fructosamine kinase

Gene name frlD
Synonyms yurL
Essential no
Product fructosamine kinase
Function metabolism of sugar amines
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 30 kDa, 4.909
Gene length, protein length 852 bp, 284 aa
Immediate neighbours frlR, frlM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YurL context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

utilization of specific carbon sources, utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

CodY regulon, FrlR regulon

The gene

Basic information

  • Locus tag: BSU32570

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: carbohydrate kinase pfkB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • frlB: repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • frlB: induced in the presence of fructosamine (FrlR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional references: PubMed