Difference between revisions of "Fni"
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* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1P0N 1P0N] (complex with FMN), [http://www.rcsb.org/pdb/explore.do?structureId=1P0K 1P0K] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1P0N 1P0N] (complex with FMN), [http://www.rcsb.org/pdb/explore.do?structureId=1P0K 1P0K] | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P50740 P50740] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22870] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22870] | ||
Revision as of 13:21, 20 July 2009
- Description: isopentenyl diphosphate isomerase
| Gene name | fni |
| Synonyms | ypgA |
| Essential | no |
| Product | isopentenyl diphosphate isomerase |
| Function | lipid metabolism |
| MW, pI | 22 kDa, 6.101 |
| Gene length, protein length | 636 bp, 212 aa |
| Immediate neighbours | yphA, ypfD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU22870
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Isopentenyl diphosphate = dimethylallyl diphosphate (according to Swiss-Prot)
- Protein family: IPP isomerase type 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: P50740
- KEGG entry: [2]
- E.C. number: 5.3.3.2
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mattijs K Julsing, Michael Rijpkema, Herman J Woerdenbag, Wim J Quax, Oliver Kayser
Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis.
Appl Microbiol Biotechnol: 2007, 75(6);1377-84
[PubMed:17458547]
[WorldCat.org]
[DOI]
(P p)
Motoki Takagi, Kazuhide Kaneda, Tomohiro Shimizu, Yoichi Hayakawa, Haruo Seto, Tomohisa Kuzuyama
Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase.
Biosci Biotechnol Biochem: 2004, 68(1);132-7
[PubMed:14745175]
[WorldCat.org]
[DOI]
(P p)
Stefan Steinbacher, Johannes Kaiser, Stefan Gerhardt, Wolfgang Eisenreich, Robert Huber, Adelbert Bacher, Felix Rohdich
Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis.
J Mol Biol: 2003, 329(5);973-82
[PubMed:12798687]
[WorldCat.org]
[DOI]
(P p)
