Difference between revisions of "FliG"
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| − | * '''Description:''' flagellar motor switch protein, physically transduces force from [[MotA]] to the rotation of [[FliF]] <br/><br/> | + | * '''Description:''' flagellar basal-body protein, membrane anchor of the basal body, flagellar motor switch protein, physically transduces force from [[MotA]] to the rotation of [[FliF]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
* mucoid phenotype due to the overproduction of poly-gamma-glutamate {{PubMed|24296669}} | * mucoid phenotype due to the overproduction of poly-gamma-glutamate {{PubMed|24296669}} | ||
| + | * no secretion of [[FlgM]], permanent inhibition of [[SigD]] {{PubMed|25313396}} | ||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** [[EpsE]]-[[FliG]] {{PubMed|18566286}} | ** [[EpsE]]-[[FliG]] {{PubMed|18566286}} | ||
| + | ** [[FliF]]-[[FliG]] {{PubMed|25313396}} | ||
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | ||
| Line 149: | Line 149: | ||
=References= | =References= | ||
| − | <pubmed>1905667,9657996,8157612,15175317,14651647, 18566286 17850253 24296669</pubmed> | + | <pubmed>1905667,9657996,8157612,15175317,14651647, 18566286 17850253 24296669 25313396</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:01, 27 October 2014
- Description: flagellar basal-body protein, membrane anchor of the basal body, flagellar motor switch protein, physically transduces force from MotA to the rotation of FliF
| Gene name | fliG |
| Synonyms | flaA15 |
| Essential | no |
| Product | flagellar motor switch protein |
| Function | movement and chemotaxis |
| Gene expression levels in SubtiExpress: fliG | |
| Interactions involving this protein in SubtInteract: FliG | |
| MW, pI | 38 kDa, 4.46 |
| Gene length, protein length | 1014 bp, 338 aa |
| Immediate neighbours | fliF, fliH |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
motility and chemotaxis, membrane proteins
This gene is a member of the following regulons
CodY regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16220
Phenotypes of a mutant
- mucoid phenotype due to the overproduction of poly-gamma-glutamate PubMed
- no secretion of FlgM, permanent inhibition of SigD PubMed
Database entries
- BsubCyc: BSU16220
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: fliG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity: interaction with EpsE prevents energetization of the flagellum by MotA-MotB PubMed
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU16220
- Structure:
- UniProt: P23448
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
- Regulatory mechanism:
- Additional information:
- number of protein molecules per cell (minimal medium with glucose and ammonium): 250 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
