Difference between revisions of "FlhF"

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* '''Description:''' [[signal recognition particle]]-like GTPase, placement and assembly of flagella <br/><br/>
+
* '''Description:''' [[signal recognition particle]]-like GTPase, placement and assembly of flagella, control of basal body position <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1098 bp, 366 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1098 bp, 366 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flhA]]'', ''[[ylxH]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flhA]]'', ''[[flhG]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13513&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13513&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
** interaction with [[YlxH]] activates the GTPase activity of [[FlhF]] {{PubMed|22056770}}
+
** interaction with [[FlhG]] activates the GTPase activity of [[FlhF]] {{PubMed|22056770}}
  
 
* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
** [[YlxH]]-[[FlhF]] ([[YlxH]] binds the GTP-bound homodimer of [[FlhF]]) {{PubMed|22056770}}
+
** [[FlhG]]-[[FlhF]] ([[FlhG]] binds the GTP-bound homodimer of [[FlhF]]) {{PubMed|22056770}}
  
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
+
* '''[[Localization]]:'''  
 +
** cell membrane (according to Swiss-Prot)
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flhF_1709747_1710847_1 flhF] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flhF_1709747_1710847_1 flhF] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
 
** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 
** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
 
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
 
** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}

Revision as of 17:41, 30 November 2012

Gene name flhF
Synonyms
Essential no
Product signal recognition particle-like GTPase
Function placement and assembly of polar flagella
Gene expression levels in SubtiExpress: flhF
Interactions involving this protein in SubtInteract: FlhF
MW, pI 40 kDa, 8.719
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours flhA, flhG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FlhF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlhF expression.png















Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GTP-binding SRP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References