Difference between revisions of "FlhB"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fliR]]'', ''[[flhA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fliR]]'', ''[[flhA]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16380 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16380 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16380 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16380 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16380 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16380 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:flhB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:flhB_context.gif]]

Revision as of 10:14, 14 May 2013

  • Description: flagella-associated protein

Gene name flhB
Synonyms
Essential no
Product flagella-associated protein
Function movement and chemotaxis
Gene expression levels in SubtiExpress: flhB
MW, pI 40 kDa, 9.771
Gene length, protein length 1080 bp, 360 aa
Immediate neighbours fliR, flhA
Sequences Protein DNA DNA_with_flanks
Genetic context
FlhB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlhB expression.png















Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16380

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: type III secretion exporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kazuo Kobayashi
Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis.
Mol Microbiol: 2007, 66(2);395-409
[PubMed:17850253] [WorldCat.org] [DOI] (P p)

H Werhane, P Lopez, M Mendel, M Zimmer, G W Ordal, L M Márquez-Magaña
The last gene of the fla/che operon in Bacillus subtilis, ylxL, is required for maximal sigmaD function.
J Bacteriol: 2004, 186(12);4025-9
[PubMed:15175317] [WorldCat.org] [DOI] (P p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

W Estacio, S S Anna-Arriola, M Adedipe, L M Márquez-Magaña
Dual promoters are responsible for transcription initiation of the fla/che operon in Bacillus subtilis.
J Bacteriol: 1998, 180(14);3548-55
[PubMed:9657996] [WorldCat.org] [DOI] (P p)

L M Márquez-Magaña, M J Chamberlin
Characterization of the sigD transcription unit of Bacillus subtilis.
J Bacteriol: 1994, 176(8);2427-34
[PubMed:8157612] [WorldCat.org] [DOI] (P p)

P B Carpenter, A R Zuberi, G W Ordal
Bacillus subtilis flagellar proteins FliP, FliQ, FliR and FlhB are related to Shigella flexneri virulence factors.
Gene: 1993, 137(2);243-5
[PubMed:8299954] [WorldCat.org] [DOI] (P p)