FlhA

• Description: flagella-associated protein
  
  

Gene name	flhA
Synonyms
Essential	no
Product	flagella-associated protein
Function	movement and chemotaxis
MW, pI	73 kDa, 4.637
Gene length, protein length	2031 bp, 677 aa
Immediate neighbours	flhB, flhF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU16390

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FHIPEP (flagella/HR/invasion proteins export pore) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P35620

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

P B Carpenter, G W Ordal
Bacillus subtilis FlhA: a flagellar protein related to a new family of signal-transducing receptors.
Mol Microbiol: 1993, 7(5);735-43
[PubMed:8097015] [WorldCat.org] [DOI] (P p)