Difference between revisions of "FbpB"

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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed unless the cells enter an iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 16:40, 11 June 2009

  • Description: Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation

Gene name fbpB
Synonyms ydbN
Essential no
Product Fur-regulated basic protein, acts as RNA chaperone
for fsrA, response to iron limitation
Function RNA chaperone
MW, pI 6 kDa, 9.9
Gene length, protein length 177 bp, 59 aa
Immediate neighbours ydbM, fbpA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FbpA fbpB context.jpeg



The gene

Basic information

  • Locus tag: BSU04530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The sequence of the former ydbN gene was corrected, and does now contain two genes, fbpA and fbpB. PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed unless the cells enter an iron starvation (Fur) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947] [WorldCat.org] [DOI] (I p)

  1. Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD. (2008) The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. Proc Natl Acad Sci U S A. Aug 19;105(33): 11927-32. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed