Difference between revisions of "FadN"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fadA]]'', ''[[yuzL]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fadA]]'', ''[[yuzL]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32840 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32840 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32840 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32840 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32840 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32840 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yusL_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yusL_context.gif]]

Revision as of 11:13, 14 May 2013

  • Description: 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)

Gene name fadN
Synonyms yusL
Essential no
Product 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadN
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 89 kDa, 6.53
Gene length, protein length 2445 bp, 815 aa
Immediate neighbours fadA, yuzL
Sequences Protein DNA DNA_with_flanks
Genetic context
YusL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadN expression.png



















Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

CcpA regulon, FadR regulon, SdpR regulon

The gene

Basic information

  • Locus tag: BSU32840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH (according to Swiss-Prot)
  • Protein family: 3-hydroxyacyl-CoA dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)

José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086] [WorldCat.org] [DOI] (I p)