FadF

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  • Description: similar to iron-sulphur-binding reductase

Gene name fadF
Synonyms ywjF
Essential no
Product unknown
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadF
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 79 kDa, 6.526
Gene length, protein length 2115 bp, 705 aa
Immediate neighbours acdA, ywjE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwjF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadF expression.png




























Categories containing this gene/protein

utilization of lipids, membrane proteins

This gene is a member of the following regulons

FadR regulon

The gene

Basic information

  • Locus tag: BSU37180

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): contains an iron-sulfur cluster
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the absence of long-chain fatty acids (FadR) PubMed
    • repressed by glucose (5-fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)