Difference between revisions of "FadB"

From SubtiWiki
Jump to: navigation, search
(Expression and regulation)
Line 117: Line 117:
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
 +
** ''[[lcfA]]'': [[SigA]] {{PubMed|21398533}}
 
** ''[[fadR]]'': [[SigA]] {{PubMed|17189250}}
 
** ''[[fadR]]'': [[SigA]] {{PubMed|17189250}}
  

Revision as of 15:44, 23 August 2012

  • Description: 3-hydroxyacyl-CoA dehydratase

Gene name fadB
Synonyms ysiB
Essential no
Product 3-hydroxyacyl-CoA dehydratase
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadB
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 27 kDa, 4.951
Gene length, protein length 774 bp, 258 aa
Immediate neighbours etfB, fadR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YsiB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadB expression.png




























Categories containing this gene/protein

utilization of lipids, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, FadR regulon

The gene

Basic information

  • Locus tag: BSU28540

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O (according to Swiss-Prot)
  • Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-230 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3PEA (from B. anthracis, 49% identity, 66% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed