Difference between revisions of "FadB"

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Line 80: Line 80:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94549 P94549]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94549 P94549]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28540]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28540 BSU28540]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.2.1.17 4.2.1.17]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.2.1.17 4.2.1.17]

Revision as of 03:26, 14 May 2009

  • Description: 3-hydroxyacyl-CoA dehydratase

Gene name fadB
Synonyms ysiB
Essential no
Product 3-hydroxyacyl-CoA dehydratase
Function fatty acid degradation
MW, pI 27 kDa, 4.951
Gene length, protein length 774 bp, 258 aa
Immediate neighbours etfB, fadR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YsiB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (3.8-fold) (CcpA) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
  2. Matsuoka H, Hirooka K, Fujita Y. (2007) Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation. J Biol Chem. Feb 23;282(8): 5180-94. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed