Difference between revisions of "EtfB"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[FadR regulon]]}}
+
{{SubtiWiki regulon|[[CcpA regulon]]}}, {{SubtiWiki regulon|[[FadR regulon]]}}
  
 
=The gene=
 
=The gene=
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* '''Regulation:'''  
 
* '''Regulation:'''  
 
** induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}}
 
** induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}}
 +
** subject to carbon catabolite repression ([[CcpA]]-[[PtsH|HPr(Ser-P)]] {{PubMed|21398533}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[FadR]]: transcription repression {{PubMed|17189250}}
 
** [[FadR]]: transcription repression {{PubMed|17189250}}
 +
** [[CcpA]]-[[PtsH|HPr(Ser-P)]]: transcription repression {{PubMed|21398533}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
 
+
'''Additional publications:''' {{PubMed|21398533}}
 
<pubmed>17189250, 17919287, 17085570</pubmed>
 
<pubmed>17189250, 17919287, 17085570</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:57, 19 March 2011

  • Description: electron transfer flavoprotein (beta subunit)

Gene name etfB
Synonyms
Essential no
Product electron transfer flavoprotein (beta subunit)
Function fatty acid degradation
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 28 kDa, 4.187
Gene length, protein length 771 bp, 257 aa
Immediate neighbours etfA, fadB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
EtfB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

electron transport/ other, utilization of lipids

This gene is a member of the following regulons

CcpA regulon, FadR regulon

The gene

Basic information

  • Locus tag: BSU28530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ETF beta-subunit/fixA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions: EtfA-EtfB (based on function)
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

Chiara Barabesi, Alessandro Galizzi, Giorgio Mastromei, Mila Rossi, Elena Tamburini, Brunella Perito
Bacillus subtilis gene cluster involved in calcium carbonate biomineralization.
J Bacteriol: 2007, 189(1);228-35
[PubMed:17085570] [WorldCat.org] [DOI] (P p)