Essential genes

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  • There are currently 253 essential protein-coding genes known in B. subtilis.

Genes in this functional category

Protein synthesis, secretion and quality control

Aminoacyl-tRNA synthetases

Ribosomal proteins

Ribosome assembly

rRNA modification/maturation

tRNA modification/maturation

Translation factors

Translation/ other

Protein secretion/ chaperones/ protein quality control

Cell envelope and cell division

Cell wall synthesis

Cell division

Cell shape

Metabolism

Central energy metabolism

Glycolysis

Biosynthesis of amino acids

Biosynthesis of lipids

Biosynthesis of nucleotides

Biosynthesis of cofactors

Metal ion transport

Biosynthesis of iron-sulphur clusters

Phosphate metabolism


DNA replication and chromosome maintenance

DNA replication

Chromosome condensation/ segregation

RNA synthesis and degradation

Transcription

RNases

Protective functions

Unknown

The list of essential genes according to Kobayashi et al. (2003)

Important original publications


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