Difference between revisions of "Essential genes"

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(Genes in this functional category)
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== Genes in this functional category ==
 
== Genes in this functional category ==
=== Metabolism ===
 
==== Central energy metabolism ====
 
* ''[[odhB]]''
 
* ''[[pdhA]]''
 
* ''[[resB]]''
 
* ''[[resC]]''
 
* ''[[yumC]]''
 
==== Glycolysis ====
 
* ''[[eno]]''
 
* ''[[gapA]]''
 
* ''[[pgm]]''
 
==== Biosynthesis of amino acids ====
 
* ''[[glyA]]''
 
* ''[[metK]]''
 
 
==== Biosynthesis of lipids ====
 
* ''[[accA]]''
 
* ''[[accB]]''
 
* ''[[accC]]''
 
* ''[[accD]]''
 
* ''[[acpA]]''
 
* ''[[acpS]]''
 
* ''[[cdsA]]''
 
* ''[[fabD]]''
 
* ''[[fabF]]''
 
* ''[[fabG]]''
 
* ''[[gpsA]]''
 
* ''[[ispC]]''
 
* ''[[ispD]]''
 
* ''[[ispE]]''
 
* ''[[ispF]]''
 
* ''[[ispG]]''
 
* ''[[ispH]]''
 
* ''[[pgsA]]''
 
* ''[[plsC]]''
 
* ''[[plsX]]''
 
* ''[[plsY]]''
 
* ''[[ywpB]]''
 
 
==== Biosynthesis of nucleotides ====
 
* ''[[adk]]''
 
* ''[[cmk]]''
 
* ''[[gmk]]''
 
* ''[[guaB]]''
 
* ''[[hprT]]''
 
* ''[[nrdE]]''
 
* ''[[nrdF]]''
 
* ''[[nrdI]]''
 
* ''[[prs]]''
 
* ''[[pyrG]]''
 
* ''[[tmk]]''
 
 
==== Biosynthesis of cofactors ====
 
* ''[[birA]]''
 
* ''[[dfrA]]''
 
* ''[[dxs]]''
 
* ''[[hepS]]''
 
* ''[[hepT]]''
 
* ''[[menA]]''
 
* ''[[menB]]''
 
* ''[[menC]]''
 
* ''[[menD]]''
 
* ''[[menE]]''
 
* ''[[menH]]''
 
* ''[[nadD]]''
 
* ''[[nadE]]''
 
* ''[[nadF]]''
 
* ''[[ribC]]''
 
* ''[[ytaG]]''
 
 
==== Metal ion transport ====
 
* ''[[mntA]]''
 
* ''[[mrpA]]''
 
* ''[[mrpB]]''
 
* ''[[mrpC]]''
 
* ''[[mrpD]]''
 
* ''[[mrpF]]''
 
 
==== Biosynthesis of iron-sulphur clusters ====
 
* ''[[sufB]]''
 
* ''[[sufC]]''
 
* ''[[sufD]]''
 
* ''[[sufS]]''
 
* ''[[sufU]]''
 
 
==== Phosphate metabolism ====
 
* ''[[ppaC]]''
 
* ''[[yfkN]]''
 
 
 
=== Protein synthesis, secretion and quality control ===
 
=== Protein synthesis, secretion and quality control ===
 
 
==== Aminoacyl-tRNA synthetases ====
 
==== Aminoacyl-tRNA synthetases ====
 
* ''[[alaS]]''
 
* ''[[alaS]]''
Line 272: Line 182:
 
* ''[[mreD]]''
 
* ''[[mreD]]''
 
* ''[[rodA]]''
 
* ''[[rodA]]''
 +
 +
=== Metabolism ===
 +
==== Central energy metabolism ====
 +
* ''[[odhB]]''
 +
* ''[[pdhA]]''
 +
* ''[[resB]]''
 +
* ''[[resC]]''
 +
* ''[[yumC]]''
 +
 +
==== Glycolysis ====
 +
* ''[[eno]]''
 +
* ''[[gapA]]''
 +
* ''[[pgm]]''
 +
 +
==== Biosynthesis of amino acids ====
 +
* ''[[glyA]]''
 +
* ''[[metK]]''
 +
 +
==== Biosynthesis of lipids ====
 +
* ''[[accA]]''
 +
* ''[[accB]]''
 +
* ''[[accC]]''
 +
* ''[[accD]]''
 +
* ''[[acpA]]''
 +
* ''[[acpS]]''
 +
* ''[[cdsA]]''
 +
* ''[[fabD]]''
 +
* ''[[fabF]]''
 +
* ''[[fabG]]''
 +
* ''[[gpsA]]''
 +
* ''[[ispC]]''
 +
* ''[[ispD]]''
 +
* ''[[ispE]]''
 +
* ''[[ispF]]''
 +
* ''[[ispG]]''
 +
* ''[[ispH]]''
 +
* ''[[pgsA]]''
 +
* ''[[plsC]]''
 +
* ''[[plsX]]''
 +
* ''[[plsY]]''
 +
* ''[[ywpB]]''
 +
 +
==== Biosynthesis of nucleotides ====
 +
* ''[[adk]]''
 +
* ''[[cmk]]''
 +
* ''[[gmk]]''
 +
* ''[[guaB]]''
 +
* ''[[hprT]]''
 +
* ''[[nrdE]]''
 +
* ''[[nrdF]]''
 +
* ''[[nrdI]]''
 +
* ''[[prs]]''
 +
* ''[[pyrG]]''
 +
* ''[[tmk]]''
 +
 +
==== Biosynthesis of cofactors ====
 +
* ''[[birA]]''
 +
* ''[[dfrA]]''
 +
* ''[[dxs]]''
 +
* ''[[hepS]]''
 +
* ''[[hepT]]''
 +
* ''[[menA]]''
 +
* ''[[menB]]''
 +
* ''[[menC]]''
 +
* ''[[menD]]''
 +
* ''[[menE]]''
 +
* ''[[menH]]''
 +
* ''[[nadD]]''
 +
* ''[[nadE]]''
 +
* ''[[nadF]]''
 +
* ''[[ribC]]''
 +
* ''[[ytaG]]''
 +
 +
==== Metal ion transport ====
 +
* ''[[mntA]]''
 +
* ''[[mrpA]]''
 +
* ''[[mrpB]]''
 +
* ''[[mrpC]]''
 +
* ''[[mrpD]]''
 +
* ''[[mrpF]]''
 +
 +
==== Biosynthesis of iron-sulphur clusters ====
 +
* ''[[sufB]]''
 +
* ''[[sufC]]''
 +
* ''[[sufD]]''
 +
* ''[[sufS]]''
 +
* ''[[sufU]]''
 +
 +
==== Phosphate metabolism ====
 +
* ''[[ppaC]]''
 +
* ''[[yfkN]]''
 +
  
 
=== DNA replication and chromosome maintenance ===
 
=== DNA replication and chromosome maintenance ===

Revision as of 13:17, 12 September 2013

Parent category
Neighbouring categories
Related categories

none

Genes in this functional category

Protein synthesis, secretion and quality control

Aminoacyl-tRNA synthetases

Ribosomal proteins

Ribosome assembly

rRNA modification/maturation

tRNA modification/maturation

Translation factors

Translation/ other

Protein secretion/ chaperones/ protein quality control

Cell envelope and cell division

Cell wall synthesis

Cell division

Cell shape

Metabolism

Central energy metabolism

Glycolysis

Biosynthesis of amino acids

Biosynthesis of lipids

Biosynthesis of nucleotides

Biosynthesis of cofactors

Metal ion transport

Biosynthesis of iron-sulphur clusters

Phosphate metabolism


DNA replication and chromosome maintenance

DNA replication

Chromosome condensation/ segregation

RNA synthesis and degradation

Transcription

RNases

Protective functions

Unknown

The list of essential genes according to Kobayashi et al. (2003)

Important original publications

Fabian M Commichau, Nico Pietack, Jörg Stülke
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
Mol Biosyst: 2013, 9(6);1068-75
[PubMed:23420519] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)

Alison Hunt, Joy P Rawlins, Helena B Thomaides, Jeff Errington
Functional analysis of 11 putative essential genes in Bacillus subtilis.
Microbiology (Reading): 2006, 152(Pt 10);2895-2907
[PubMed:17005971] [WorldCat.org] [DOI] (P p)

K Kobayashi, S D Ehrlich, A Albertini, G Amati, K K Andersen, M Arnaud, K Asai, S Ashikaga, S Aymerich, P Bessieres, F Boland, S C Brignell, S Bron, K Bunai, J Chapuis, L C Christiansen, A Danchin, M Débarbouille, E Dervyn, E Deuerling, K Devine, S K Devine, O Dreesen, J Errington, S Fillinger, S J Foster, Y Fujita, A Galizzi, R Gardan, C Eschevins, T Fukushima, K Haga, C R Harwood, M Hecker, D Hosoya, M F Hullo, H Kakeshita, D Karamata, Y Kasahara, F Kawamura, K Koga, P Koski, R Kuwana, D Imamura, M Ishimaru, S Ishikawa, I Ishio, D Le Coq, A Masson, C Mauël, R Meima, R P Mellado, A Moir, S Moriya, E Nagakawa, H Nanamiya, S Nakai, P Nygaard, M Ogura, T Ohanan, M O'Reilly, M O'Rourke, Z Pragai, H M Pooley, G Rapoport, J P Rawlins, L A Rivas, C Rivolta, A Sadaie, Y Sadaie, M Sarvas, T Sato, H H Saxild, E Scanlan, W Schumann, J F M L Seegers, J Sekiguchi, A Sekowska, S J Séror, M Simon, P Stragier, R Studer, H Takamatsu, T Tanaka, M Takeuchi, H B Thomaides, V Vagner, J M van Dijl, K Watabe, A Wipat, H Yamamoto, M Yamamoto, Y Yamamoto, K Yamane, K Yata, K Yoshida, H Yoshikawa, U Zuber, N Ogasawara
Essential Bacillus subtilis genes.
Proc Natl Acad Sci U S A: 2003, 100(8);4678-83
[PubMed:12682299] [WorldCat.org] [DOI] (P p)


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