Difference between revisions of "EcsB"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ecsA]]'', ''[[ecsC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ecsA]]'', ''[[ecsC]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10050 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10050 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ecsB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ecsB_context.gif]]

Revision as of 09:50, 14 May 2013

Gene name ecsB
Synonyms prsT, yhaC
Essential no
Product ABC transporter ( membrane protein)
Function regulation of the secretion apparatus and of intra-membrane proteolysis
Gene expression levels in SubtiExpress: ecsB
Interactions involving this protein in SubtInteract: EcsB
MW, pI 47 kDa, 10.181
Gene length, protein length 1224 bp, 408 aa
Immediate neighbours ecsA, ecsC
Sequences Protein DNA DNA_with_flanks
Genetic context
EcsB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EcsB expression.png
























Categories containing this gene/protein

ABC transporters, protein secretion, sigma factors and their control, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Janine Heinrich, Tuula Lundén, Vesa P Kontinen, Thomas Wiegert
The Bacillus subtilis ABC transporter EcsAB influences intramembrane proteolysis through RasP.
Microbiology (Reading): 2008, 154(Pt 7);1989-1997
[PubMed:18599827] [WorldCat.org] [DOI] (P p)

Steven S Branda, José Eduardo González-Pastor, Etienne Dervyn, S Dusko Ehrlich, Richard Losick, Roberto Kolter
Genes involved in formation of structured multicellular communities by Bacillus subtilis.
J Bacteriol: 2004, 186(12);3970-9
[PubMed:15175311] [WorldCat.org] [DOI] (P p)

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

S Leskelä, E Wahlström, H L Hyyryläinen, M Jacobs, A Palva, M Sarvas, V P Kontinen
Ecs, an ABC transporter of Bacillus subtilis: dual signal transduction functions affecting expression of secreted proteins as well as their secretion.
Mol Microbiol: 1999, 31(2);533-43
[PubMed:10027970] [WorldCat.org] [DOI] (P p)

Soile Leskelä, Vesa P Kontinen, Matti Sarvas
Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC transporter with a role in exoprotein production, sporulation and competence.
Microbiology (Reading): 1996, 142 ( Pt 1);71-77
[PubMed:8581172] [WorldCat.org] [DOI] (P p)