EbrA

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  • Description: multidrug efflux transporter

Gene name ebrA
Synonyms
Essential no
Product multidrug efflux transporter
Function multidrug resistance
Gene expression levels in SubtiExpress: ebrA
Interactions involving this protein in SubtInteract: EbrA
MW, pI 11 kDa, 9.373
Gene length, protein length 315 bp, 105 aa
Immediate neighbours ebrB, ymaG
Sequences Protein DNA DNA_with_flanks
Genetic context
EbrA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EbrA expression.png

























Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17300

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): EbrB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)