EbrA

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  • Description: multidrug efflux transporter

Gene name ebrA
Synonyms
Essential no
Product multidrug efflux transporter
Function multidrug resistance
Gene expression levels in SubtiExpress: ebrA
Interactions involving this protein in SubtInteract: EbrA
MW, pI 11 kDa, 9.373
Gene length, protein length 315 bp, 105 aa
Immediate neighbours ebrB, ymaG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
EbrA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EbrA expression.png

























Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17300

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): EbrB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)