Difference between revisions of "EbrA"
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| − | * '''Description:''' multidrug | + | * '''Description:''' multidrug efflux transporter<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || multidrug | + | |style="background:#ABCDEF;" align="center"| '''Product''' || multidrug efflux transporter |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance | |style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance | ||
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* '''Protein family:''' | * '''Protein family:''' | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[EbrB]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[EbrA]]-[[EbrB]] {{PubMed|17417881}} |
| − | * '''Localization:''' cell membrane | + | * '''Localization:''' cell membrane {{PubMed|17417881}} |
=== Database entries === | === Database entries === | ||
| Line 117: | Line 117: | ||
=References= | =References= | ||
| − | + | <pubmed>17417881 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:57, 28 December 2009
- Description: multidrug efflux transporter
| Gene name | ebrA |
| Synonyms | |
| Essential | no |
| Product | multidrug efflux transporter |
| Function | multidrug resistance |
| MW, pI | 11 kDa, 9.373 |
| Gene length, protein length | 315 bp, 105 aa |
| Immediate neighbours | ebrB, ymaF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU17300
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): EbrB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: O31792
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881]
[WorldCat.org]
[DOI]
(P p)
