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| − | * '''Description:''' [[small RNAs|small regulatory RNA]] controlling [[AhrC]] expression, peptide controlling the stability of the ''[[cggR]]-[[gapA]]'' mRNA <br/><br/>
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| − | {| align="right" border="1" cellpadding="2"
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| − | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| − | |''sr1''
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ykzW ''
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || [[small RNAs|small regulatory RNA]]/ regulatory peptide
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of arginine metabolism and glycolysis
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| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4.4 kDa, 3.89
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| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 205 bp (RNA), 120 bp (ORF), 39 aa
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[slp]]'', ''[[speA]]''
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| − | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/sr1_nucleotide.txt Gene sequence ]'''
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| − | |style="background:#FAF8CC;" align="center"|
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| − | |colspan="2" | '''Genetic context''' <br/> [[Image:sr1_context.gif]]
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| − | |}
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| − | __TOC__
| + | [[File:Example.jpg]] |
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| − | <br/><br/><br/>
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| − | =The gene=
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| − | === Basic information ===
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| − | * '''Locus tag:'''
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| − | ===Phenotypes of a mutant ===
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| − | === Database entries ===
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| − | * '''DBTBS entry:''' no entry
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| − | === Additional information===
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| − | Located between the ''[[slp]]'' and ''[[speA]]'' genes.
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| − | = Categories containing this gene/protein =
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| − | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
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| − | {{SubtiWiki category|[[utilization of amino acids]]}},
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| − | {{SubtiWiki category|[[ncRNA]]}}
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| − | =The RNA=
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| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[ahrC]]'' mRNA and inhibits [[AhrC]] translation. [http://www.ncbi.nlm.nih.gov/sites/entrez/17020585 PubMed]
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| − | === Extended information on the RNA===
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| − | * '''Kinetic information'''
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| − | * '''Interactions:''' Binds ''[[ahrC]]'' mRNA [http://www.ncbi.nlm.nih.gov/sites/entrez/17020585 PubMed]
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| − | * '''Localization'''
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| − | === Database entries ===
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| − | * '''Structure''':
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| − | === Additional information===
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| − | Information on the structure of the RNA can be found in [http://www.ncbi.nlm.nih.gov/pubmed/17020585?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Heidrich ''et al''., 2006 ]
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| − | =The peptide=
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| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:''' the peptide controls the stability of the ''[[cggR]]-[[gapA]]'' mRNA {{PubMed|20444087}}
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| − | * '''Protein family:''' the peptide is conserved in bacilli
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| − | * '''Paralogous protein(s):'''
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| − | === Extended information on the protein ===
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| − | * '''Kinetic information:'''
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| − | * '''Domains:'''
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| − | * '''Modification:'''
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| − | * '''Cofactor(s):'''
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| − | * '''Effectors of protein activity:'''
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| − | * '''Interactions:'''
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| − | ** [[GapA]]-[[YkzW]] {{PubMed|20444087}}
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| − | * '''Localization:'''
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| − | === Database entries ===
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| − | * '''Structure:'''
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| − | * '''UniProt:''' [http://www.uniprot.org/uniprot/C0H410 C0H410]
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| − | * '''KEGG entry:'''
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| − | * '''E.C. number:'''
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| − | === Additional information===
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| − | =Expression and regulation=
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| − | * '''Operon:''' sr1 [http://www.ncbi.nlm.nih.gov/sites/entrez/16164558 PubMed]
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| − | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16164558 PubMed]
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| − | * '''Regulation:''' Repressed in the presence of glucose by [[CcpN]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16164558 PubMed]
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| − | * '''Regulatory mechanism:''' transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16164558 PubMed]
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| − | * '''Additional information:'''
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| − | =Biological materials =
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| − | * '''Mutant:''' 168 sr1::cat, available in [[Brantl]] lab
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| − | * '''Expression vector:'''
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| − | * '''lacZ fusion:'''
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| − | =Labs working on this gene/protein=
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| − | [[Sabine Brantl |Sabine Brantl]], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]
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| − | =Your additional remarks=
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| − | =References=
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| − | <pubmed>16164558 17020585 17576690, 20444087 </pubmed>
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| − | [[Category:Protein-coding genes]]
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