Difference between revisions of "DynA"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Additional information:'''  
 
* '''Additional information:'''  
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** A [[ncRNA]] is predicted between ''[[dynA]]'' and ''[[bpsB]]'' {{PubMed|20525796}}
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
<pubmed> 8396117 21205012 </pubmed>
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<pubmed> 8396117 21205012 20525796</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:14, 4 May 2011

  • Description: dynamin-like protein, mediates membrane fusion

Gene name dynA
Synonyms ypbR
Essential no
Product dynamin-like protein
Function fusion of membranes
MW, pI 137 kDa, 5.724
Gene length, protein length 3579 bp, 1193 aa
Immediate neighbours ypbS, fbpC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YpbR context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

membrane dynamics, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag: BSU22030

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: mediates nucleotide independent membrane fusion in vitro PubMed
  • Protein family: gerABKA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two separate dynamin-like subunits and GTPase domains PubMed
  • Modification:
  • Effectors of protein activity:
  • Interactions: forms oligomers PubMed
  • Localization: associated to the membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of iron (Fur) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Frank Bürmann, Nina Ebert, Suey van Baarle, Marc Bramkamp
A bacterial dynamin-like protein mediating nucleotide-independent membrane fusion.
Mol Microbiol: 2011, 79(5);1294-304
[PubMed:21205012] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

L Chen, L P James, J D Helmann
Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions.
J Bacteriol: 1993, 175(17);5428-37
[PubMed:8396117] [WorldCat.org] [DOI] (P p)