dtpT

168

proton-dependent di- and tripeptide transporter

locus: BSU_03670

Molecular weight: 53.11 kDa

pI: 9.92

Protein length: 492 aa

Gene length: 1479 bp

function: uptake of di- and tripeptides

product: peptide transporter

essential: no

synonyms: dtpT, yclF

List of homologs in different organisms, belongs to COG3104 (Galperin et al., 2021)

Gene

Coordinates: 416,235  417,713

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The protein

Protein family

• PTR2/POT transporter (TC 2.A.17) family (single member, according to UniProt)

Structure

• [PDB|4IKV], the protein from ''Geobacillus kaustophilus'' (65% identity, 87% similarity), [Pubmed|23798427]
• [AF|P94408]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

additional information

• the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]

Biological materials

Mutant

• BKE03670 ([gene|819D6C5489F1F3FF63B69162EFB6581A1366F45E|dtpT]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03670 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC,  downstream forward: _UP4_TAATCAGAAACAGCCCGCGG
• BKK03670 ([gene|819D6C5489F1F3FF63B69162EFB6581A1366F45E|dtpT]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03670 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC,  downstream forward: _UP4_TAATCAGAAACAGCCCGCGG

References

• 11717292,8458848,23798427,25966844,25755103,26883633