Difference between revisions of "Drm"
| Line 20: | Line 20: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1182 bp, 394 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1182 bp, 394 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pupG]]'', ''[[ripX]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14282]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14282]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 92: | Line 92: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[drm]]-[[pupG]]'' {{PubMed|10537218}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10537218}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in the presence of nucleosides (deoxyribose 5-phosphate and ribose 5-phosphate act as molecular inducers) {{PubMed|10537218}} | ||
| + | ** subject to repression by glucose {{PubMed|10537218}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 121: | Line 123: | ||
=References= | =References= | ||
| + | <pubmed> 10537218</pubmed> | ||
Revision as of 09:17, 13 July 2009
- Description: phosphopentomutase
| Gene name | drm |
| Synonyms | yqkN |
| Essential | no |
| Product | phosphopentomutase |
| Function | utilization of deoxyribose |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleoside catabolism, Nucleotides (regulation) | |
| MW, pI | 43 kDa, 4.974 |
| Gene length, protein length | 1182 bp, 394 aa |
| Immediate neighbours | pupG, ripX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU23500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate (according to Swiss-Prot)
- Protein family: phosphopentomutase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P46353
- KEGG entry: [3]
- E.C. number: 5.4.2.7
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
R Schuch, A Garibian, H H Saxild, P J Piggot, P Nygaard
Nucleosides as a carbon source in Bacillus subtilis: characterization of the drm-pupG operon.
Microbiology (Reading): 1999, 145 ( Pt 10);2957-66
[PubMed:10537218]
[WorldCat.org]
[DOI]
(P p)
